Description

4-Butoxy-2,6-Difluoroaniline is a specialized aromatic amine derivative featuring both alkoxy and fluorine substituents, which impart unique electronic and steric properties. This compound serves as a high-value pharmaceutical intermediate and a versatile building block in advanced organic synthesis. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a difluoroaniline core structure.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Acts as a building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs), due to its aromaticity and substituent effects.
• Dye & Pigment Manufacturing: Employed in the synthesis of specialized dyes and pigments, where the aniline moiety is crucial for color development.
• Polymer Modification: Serves as a monomer or additive to introduce specific functionalities into polymer chains, improving material properties.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination) for constructing complex nitrogen-containing compounds.

Basic Information

Product Name	4-Butoxy-2,6-Difluoroaniline
CAS No.	1373920-83-2
Molecular Formula	C₁₀H₁₃F₂NO
Molecular Weight	201.21 g/mol
Synonyms	2,6-Difluoro-4-butoxyaniline; 4-(Butoxy)-2,6-difluorobenzenamine; 1-Amino-3,5-difluoro-4-butoxybenzene; Benzenamine, 4-(butoxy)-2,6-difluoro-; 4-Butoxy-2,6-difluorophenylamine; 2,6-Difluoro-4-n-butoxyaniline; Aniline, 4-butoxy-2,6-difluoro-
EINECS	Contact for details

Quality Control

Our 4-Butoxy-2,6-Difluoroaniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment. We are committed to meeting the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.