Description

2-Chloro-5-(Pentafluorosulfur)Benzylalcohol is a high-value fluorinated aromatic building block characterized by the unique combination of a chloro substituent and a pentafluorosulfur (SF5) group on the benzene ring. This compound matters for its role as a critical intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where the SF5 moiety is prized for its high electronegativity, lipophilicity, and metabolic stability. It is primarily needed by research chemists and process development teams in the pharmaceutical, agrochemical, and specialty materials sectors for creating novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly where the SF5 group is used as a bioisostere for trifluoromethyl (CF3) or other groups to improve potency and pharmacokinetics.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides that require high biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials, leveraging the SF5 group's influence on molecular polarity and stability.
• Polymer & Resin Modifier: Incorporated into specialty polymers to enhance chemical resistance, thermal stability, and surface properties.
• Organic Synthesis & Catalysis Research: Employed in academic and industrial R&D for studying novel fluorination reactions and as a ligand precursor in catalyst design.
• Dye & Pigment Intermediate: Used in the synthesis of specialized fluorinated dyes with unique color fastness and solubility profiles.

Basic Information

Product Name	2-Chloro-5-(Pentafluorosulfur)Benzylalcohol
CAS No.	1373920-80-9
Molecular Formula	C7H4ClF5OS
Molecular Weight	266.62 g/mol
Synonyms	(2-Chloro-5-(pentafluoro-λ6-sulfanyl)phenyl)methanol; 2-Chloro-α-(pentafluorosulfur)benzyl alcohol; 1-(Chloro-5-(SF5))benzyl alcohol; 2-Chloro-5-SF5-Benzyl alcohol; SF5-Benzyl Alcohol Derivative; Benzyl alcohol, 2-chloro-5-(pentafluorosulfur)-; CAS 1373920-80-9
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-(Pentafluorosulfur)Benzylalcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We support custom synthesis and can tailor specifications to meet specific project needs, including compliance with relevant guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.