Description

3-(2-Fluoro-5-Methylphenyl)Aniline, Hcl is a high-purity, halogenated aniline derivative, specifically the hydrochloride salt of a fluorinated and methylated aromatic amine. This compound serves as a critical pharmaceutical intermediate and building block in advanced organic synthesis, enabling the construction of complex molecules with tailored properties. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and material science industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its fluorinated aromatic structure for enhanced bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of advanced polymers, liquid crystals, and organic electronic materials due to its aromatic and halogenated nature.
• Chemical Biology Probes: Acts as a building block for fluorescent tags, photoaffinity labels, and other molecular probes used in biochemical research.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP conditions.

Basic Information

Item	Details
Product Name	3-(2-Fluoro-5-Methylphenyl)Aniline, Hcl
CAS No.	1373233-03-4
Molecular Formula	C13H13ClFN
Molecular Weight	237.70 g/mol
Synonyms	3-(2-Fluoro-5-methylphenyl)aniline hydrochloride; 3-Amino-2'-fluoro-5'-methylbiphenyl hydrochloride; 2-Fluoro-5-methyl-[1,1'-biphenyl]-3-amine hydrochloride; N-(2-Fluoro-5-methylphenyl)aniline hydrochloride; (2-Fluoro-5-methylphenyl)(3-aminophenyl)amine hydrochloride; 3-(2-Fluoro-5-methyl-phenyl)-phenylamine hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 3-(2-Fluoro-5-Methylphenyl)Aniline, Hcl is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.