Description

1H-Pyrazolo[4,3-D]Pyrimidine, 7-Bromo- CAS NO 1373223-77-8 is a high-purity, advanced pharmaceutical intermediate belonging to the pyrazolopyrimidine class of heterocyclic compounds. This compound serves as a critical building block in the synthesis of novel, targeted therapeutic agents, particularly in oncology and kinase inhibitor research. It is essential for medicinal chemistry R&D teams and fine chemical manufacturers engaged in developing next-generation small molecule drugs.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of kinase inhibitors targeting various cancers and inflammatory diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel drug candidates.
• Biochemical Tool Compound: Serves as a precursor for labeled probes and biochemical assay reagents in life science research.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to construct complex molecular architectures with specific biological activity.
• Contract Development and Manufacturing (CDMO): Supplied to CDMOs for scale-up and cGMP production of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and pharmacology projects.

Basic Information

Product Name	1H-Pyrazolo[4,3-D]Pyrimidine, 7-Bromo-
CAS No.	1373223-77-8
Molecular Formula	C5H3BrN4
Molecular Weight	198.99 g/mol
Synonyms	7-Bromo-1H-pyrazolo[4,3-d]pyrimidine; 7-Bromo-1H-pyrazolo[4,3-d]pyrimidine; 7-Bromo-1H-pyrazolo[4,3-d]pyrimidine; 7-Bromopyrazolo[4,3-d]pyrimidine; 1H-Pyrazolo[4,3-d]pyrimidine, 7-bromo-; 1373223-77-8; AKOS026712293; BRN 15211335
EINECS	Contact for details

Quality Control

Every batch of 1H-Pyrazolo[4,3-D]Pyrimidine, 7-Bromo- is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.