Description

2-Pyrrolidin-2-Yl-Pyrimidine Dihydrochloride is a high-purity, pharmaceutically relevant chemical building block and intermediate. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel drug candidates targeting a range of therapeutic areas. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and advanced chemical synthesis facilities requiring high-quality, well-characterized intermediates for lead optimization and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used in lead compound optimization and structure-activity relationship (SAR) studies for new therapeutic agents.
• Chemical Biology Probes: Serves as a core structure for developing molecular probes to study biological pathways and target validation.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening in drug discovery.
• Process Chemistry: Used in route scouting and scale-up studies for the development of efficient and scalable synthetic processes.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	2-Pyrrolidin-2-Yl-Pyrimidine Dihydrochloride
CAS No.	1373223-29-0
Molecular Formula	C8H14Cl2N4
Molecular Weight	237.13 g/mol
Synonyms	2-(Pyrimidin-2-yl)pyrrolidine dihydrochloride; Pyrimidine, 2-(2-pyrrolidinyl)-, dihydrochloride; 2-(2-Pyrimidinyl)pyrrolidine hydrochloride (1:2); 2-Pyrrolidin-2-ylpyrimidine dihydrochloride; 2-(Pyrrolidin-2-yl)pyrimidine dihydrochloride; Pyrrolidine, 2-(2-pyrimidinyl)-, dihydrochloride
EINECS	Contact for details

Quality Control

Our 2-Pyrrolidin-2-Yl-Pyrimidine Dihydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.