Description

Benzyl 2,4-Dichloro-5,6-Dihydropyrido[3,4-D]Pyrimidine-7(8H)-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel, potent kinase inhibitors and other biologically active molecules. It is primarily required by pharmaceutical R&D organizations and fine chemical manufacturers engaged in developing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of targeted cancer therapies, particularly kinase inhibitors.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Used in biochemical assays to study enzyme function and cellular signaling pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for exploratory research in organic synthesis and pharmacology.

Basic Information

Product Name	Benzyl 2,4-Dichloro-5,6-Dihydropyrido[3,4-D]Pyrimidine-7(8H)-Carboxylate
CAS No.	1370411-44-1
Molecular Formula	C15H12Cl2N2O2
Molecular Weight	323.17 g/mol
Synonyms	Benzyl 2,4-dichloro-5,6-dihydro-8H-pyrido[3,4-d]pyrimidine-7-carboxylate; 2,4-Dichloro-5,6-dihydro-8H-pyrido[3,4-d]pyrimidine-7-carboxylic acid benzyl ester; 7-Benzyloxycarbonyl-2,4-dichloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine; 1370411-44-1; Benzyl 2,4-dichloro-7,8-dihydro-5H-pyrido[3,4-d]pyrimidine-7-carboxylate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are available upon request, supporting your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.