Description

4-(3-(2H-1,2,3-Triazo-2-Yl)Phenylamino)-2-((1R,2S)-2-Aminocyclohexylamino) Pyrimidine-5-Carboxamide is a sophisticated, high-purity chemical intermediate designed for advanced research and development. This compound matters for its role as a key building block in the synthesis of novel pharmaceutical candidates, particularly in targeted therapeutic areas. It is primarily needed by R&D scientists and process chemists in the pharmaceutical, biotechnology, and fine chemical industries working on kinase inhibitors and other small-molecule drug discovery programs.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel kinase inhibitors and other targeted small-molecule therapeutics.
• Biochemical Research: Used as a reference standard or probe compound in enzymatic assays and biological pathway studies.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Process Development: Employed in scaling up synthetic routes for Active Pharmaceutical Ingredient (API) manufacturing under cGMP conditions.
• Contract Research Organizations (CROs): Supplied for custom synthesis projects and client-specific drug development programs.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and chemical biology.

Basic Information

Product Name	4-(3-(2H-1,2,3-Triazo-2-Yl)Phenylamino)-2-((1R,2S)-2-Aminocyclohexylamino) Pyrimidine-5-Carboxamide
CAS No.	1370261-96-3
Molecular Formula	C20H24N10O
Molecular Weight	420.47 g/mol
Synonyms	4-[3-(2H-1,2,3-Triazol-2-yl)anilino]-2-[(1R,2S)-2-aminocyclohexylamino]pyrimidine-5-carboxamide; (1R,2S)-N2-[5-Carbamoyl-4-[[3-(2H-1,2,3-triazol-2-yl)phenyl]amino]pyrimidin-2-yl]cyclohexane-1,2-diamine; UNII-9F8J7F4S4C; 9F8J7F4S4C; 4-(3-(2H-1,2,3-Triazol-2-yl)phenylamino)-2-((1R,2S)-2-aminocyclohexylamino)pyrimidine-5-carboxamide; 2-((1R,2S)-2-Aminocyclohexylamino)-4-(3-(2H-1,2,3-triazol-2-yl)phenylamino)pyrimidine-5-carboxamide
EINECS	Contact for details

Quality Control

Our 4-(3-(2H-1,2,3-Triazo-2-Yl)Phenylamino)-2-((1R,2S)-2-Aminocyclohexylamino) Pyrimidine-5-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements, supporting development from research to commercial scale.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.