Description

2,4-Difluoro-3-(1-methylethoxy)benzaldehyde is a high-purity, specialized aromatic aldehyde building block featuring a unique difluoro and isopropoxy substitution pattern. This compound is of significant value in advanced organic synthesis, where its distinct electronic and steric properties enable the construction of complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for use as a critical intermediate in the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated organic electronic materials for displays and lighting applications.
• Advanced Polymer Chemistry: Employed as a monomer or cross-linking agent to introduce fluorine and aldehyde functionality into specialty polymers, improving chemical and thermal resistance.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new reactions, catalysis, and material science.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the scale-up and production of client-specific target molecules in multi-step synthetic routes.

Basic Information

Product Name	2,4-Difluoro-3-(1-methylethoxy)benzaldehyde
CAS No.	1370025-56-1
Molecular Formula	C10H10F2O2
Molecular Weight	200.18 g/mol
Synonyms	3-Isopropoxy-2,4-difluorobenzaldehyde; 2,4-Difluoro-3-isopropoxybenzaldehyde; 3-(1-Methylethoxy)-2,4-difluorobenzaldehyde; Benzaldehyde, 2,4-difluoro-3-(1-methylethoxy)-; 2,4-Difluoro-3-(propan-2-yloxy)benzaldehyde; 3-(Isopropyloxy)-2,4-difluorobenzaldehyde
EINECS	Contact for details

Quality Control

Every batch of 2,4-Difluoro-3-(1-methylethoxy)benzaldehyde is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA), including results from HPLC, GC, NMR, and mass spectrometry, is supplied with each shipment to guarantee identity, purity, and consistency for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to light and potential for oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.