Description

Butanoic Acid, 2-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-4-(Methylseleno)-, (2R)- is a specialized, non-natural amino acid derivative featuring a protected amine group (Fmoc) and a unique methylseleno side chain, making it a critical building block for advanced peptide synthesis and chemical biology research. This high-purity chiral compound, designated as (2R)-, is essential for introducing selenium functionality into synthetic peptides, enabling the study of selenoproteins, redox biology, and the development of novel bioconjugates. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on peptide-based drug discovery, enzyme mimetics, and the synthesis of complex bioactive molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): As an Fmoc-protected amino acid, it serves as a key monomer for the automated, sequential assembly of selenium-containing peptides.
• Selenopeptide & Selenoprotein Research: Used to incorporate selenomethionine analogs into peptide sequences to model and study the structure and function of natural selenoproteins.
• Chemical Biology Probes: Enables the creation of labeled or tagged peptides for investigating protein-protein interactions, enzyme mechanisms, and cellular pathways.
• Pharmaceutical Intermediate: Acts as a sophisticated chiral synthon in the research and development stages of novel therapeutic peptides and peptidomimetics.
• Catalyst & Ligand Development: The organoselenium moiety can be utilized in the design of novel catalysts or metal-chelating ligands for asymmetric synthesis.
• Material Science: Potential use in creating functionalized surfaces or biomaterials with specific redox or catalytic properties.

Basic Information

Product Name	Butanoic Acid, 2-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-4-(Methylseleno)-, (2R)-
CAS No.	1369531-99-6
Molecular Formula	C20H21NO4Se
Molecular Weight	418.34 g/mol
Synonyms	(2R)-2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-4-(methylselanyl)butanoic acid; Fmoc-Sec(Me)-OH; Fmoc-(R)-4-(Methylseleno)homoalanine-OH; N-α-Fmoc-N-δ-(methylseleno)-L-homoalanine; N-α-Fmoc-S-methyl-L-selenocysteine; Fmoc-L-Sec(Me)-OH; Fmoc-protected methylselenocysteine; 2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-4-(methylseleno)butanoic acid (R-enantiomer)
EINECS	Contact for details

Quality Control

Our Butanoic Acid, 2-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-4-(Methylseleno)-, (2R)- is manufactured under strict quality management systems to ensure high chiral purity and chemical integrity, critical for sensitive peptide synthesis. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles. We adhere to cGMP guidelines where applicable for research-grade materials, ensuring traceability and consistency for our global clientele in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. Under these conditions, the product is typically stable for at least 24 months. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee (R)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.