Description

C-(4-Trifluoromethyl-Pyrimidin-5-Yl)-Methylamine is a high-purity, advanced pharmaceutical intermediate featuring a pyrimidine core substituted with a trifluoromethyl group. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring specific molecular interactions. Pharmaceutical R&D teams and fine chemical manufacturers need it to develop next-generation drugs, leveraging its unique structure to modulate potency, selectivity, and metabolic stability.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel Active Pharmaceutical Ingredients (APIs) in drug discovery and development.
• Agrochemical Research: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl-pyrimidine moiety can enhance biological activity.
• Material Science: Serves as a precursor for specialty chemicals and functional materials, including liquid crystals and organic electronic components.
• Academic & Contract Research: Employed in university and CRO laboratories for medicinal chemistry programs and structure-activity relationship (SAR) studies.
• Bioconjugation & Probe Synthesis: The amine functional group allows for its use in creating biochemical probes, diagnostic agents, and targeted drug conjugates.

Basic Information

Product Name	C-(4-Trifluoromethyl-Pyrimidin-5-Yl)-Methylamine
CAS No.	1368841-13-7
Molecular Formula	C7H8F3N3
Molecular Weight	191.16 g/mol
Synonyms	5-(Aminomethyl)-4-(trifluoromethyl)pyrimidine; (4-Trifluoromethylpyrimidin-5-yl)methanamine; 4-Trifluoromethyl-5-pyrimidinemethanamine; 5-(Aminomethyl)-4-trifluoromethylpyrimidine; 4-(Trifluoromethyl)-5-pyridinemethanamine (incorrect but common); 5-Pyrimidinemethanamine, 4-(trifluoromethyl)-; C-(4-Trifluoromethyl-Pyrimidin-5-Yl)-Methyl Amine
EINECS	Contact for details

Quality Control

Our C-(4-Trifluoromethyl-Pyrimidin-5-Yl)-Methylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.