Description

2-Chloro-7H-Pyrrolo[2,3-D]Pyrimidine-5-Carbaldehyde is a high-value heterocyclic building block, specifically a functionalized pyrrolopyrimidine derivative. This compound is critical for medicinal chemistry research and development, serving as a versatile scaffold for constructing novel small molecule therapeutics. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of kinase inhibitors and other targeted agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of advanced kinase inhibitors targeting various oncology and inflammatory disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Biochemical Probe Development: Serves as a starting material for creating labeled or tagged compounds used in biological target identification and validation.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing high-purity, complex organic molecules.
• Academic Research: Utilized in university and institutional labs for methodological development in heterocyclic chemistry and bioorganic studies.

Basic Information

Product Name	2-Chloro-7H-Pyrrolo[2,3-D]Pyrimidine-5-Carbaldehyde
CAS No.	1367868-00-5
Molecular Formula	C7H4ClN3O
Molecular Weight	181.58 g/mol
Synonyms	2-Chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carboxaldehyde; 2-Chloro-5-formyl-7H-pyrrolo[2,3-d]pyrimidine; 7H-Pyrrolo[2,3-d]pyrimidine-5-carboxaldehyde, 2-chloro-; 1367868-00-5; 2-Chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbaldehyde; 2-Chloro-5-carbaldehyde-7H-pyrrolo[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 2-Chloro-7H-Pyrrolo[2,3-D]Pyrimidine-5-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with full batch traceability are provided to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation by atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.