Description

Atrial Natriuretic Peptide (ANP) (1-28), Human, Porcine (Acetate) is a high-purity synthetic peptide fragment corresponding to the biologically active 1-28 sequence of the endogenous hormone. This compound is a critical research tool and reference standard for studying cardiovascular physiology, renal function, and hypertension. It is essential for pharmaceutical R&D, academic research, and diagnostic assay development in the life sciences sector. The product is supplied as the acetate salt to enhance stability and solubility.

Application

• Biomedical Research: Used as a reference standard and active agent in studies of natriuresis, diuresis, vasodilation, and the renin-angiotensin-aldosterone system (RAAS).
• Pharmaceutical Development: Serves as a key starting material or reference compound in the discovery and development of cardiovascular and renal therapeutics.
• Diagnostic Assays: Employed as a calibrator or control in immunoassays (e.g., ELISA, RIA) designed to measure ANP levels in biological samples.
• Cell Culture & In Vitro Studies: Applied in cell-based assays to investigate ANP receptor (NPR-A) signaling pathways and cellular responses.
• Biochemical Reagent: Utilized in enzyme studies, receptor binding assays, and other biochemical investigations.

Basic Information

Product Name	Atrial Natriuretic Peptide (ANP) (1-28), Human, Porcine (Acetate)
CAS No.	1366000-58-9
Molecular Formula	C128H205N41O39 • (C2H4O2)x
Molecular Weight	3081.4 g/mol (free acid)
Synonyms	ANP (1-28); Atriopeptin (1-28); Cardionatrin (1-28); Atrial Natriuretic Factor (1-28); ANF (1-28); hANP (1-28); Porcine ANP (1-28); Atrial Natriuretic Peptide Fragment 1-28; Auriculin A (1-28)
EINECS	Contact for details

Quality Control

Our Atrial Natriuretic Peptide (ANP) (1-28) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing purity, content, and solvent residues. The product is suitable for research and development use under current Good Manufacturing Practice (cGMP) guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by amino acid analysis)
Acetate Content	5 - 15% (by ion chromatography)
Water Content (KF)	≤ 8.0%
Single Impurity (HPLC)	≤ 2.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.