Description

6-[Bis(tert-Butoxycarbonyl)Amino]-4-Aminopyrimidine is a high-purity, protected diamine pyrimidine derivative of significant importance in advanced organic synthesis. This compound serves as a critical building block for the development of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Protecting Group Chemistry: Utilized in multi-step organic synthesis where selective protection and deprotection of amine functionalities are required.
• Heterocyclic Compound Synthesis: Serves as a versatile scaffold for constructing more complex fused pyrimidine and purine analogs.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probes: Employed in the creation of molecular probes for studying biological pathways and enzyme functions.
• Material Science: Potential monomer or precursor for specialty polymers and advanced organic materials.

Basic Information

Product Name	6-[Bis(tert-Butoxycarbonyl)Amino]-4-Aminopyrimidine
CAS No.	1364663-35-3
Molecular Formula	C14H22N4O4
Molecular Weight	310.35 g/mol
Synonyms	6-[Bis(Boc)Amino]-4-Aminopyrimidine; 4-Amino-6-[(bis(tert-butoxycarbonyl)amino)]pyrimidine; 6-(Bis(tert-butoxycarbonyl)amino)-4-pyrimidinamine; N,N-Bis(tert-butoxycarbonyl)-4-amino-6-aminopyrimidine; Boc-protected 4,6-diaminopyrimidine; 4,6-Diaminopyrimidine, N6-Bis-Boc protected; tert-Butyl [4-amino-6-[(tert-butoxycarbonyl)amino]pyrimidin-2-yl]carbamate (related); BOC-ANP
EINECS	Contact for details

Quality Control

Our 6-[Bis(tert-Butoxycarbonyl)Amino]-4-Aminopyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C (refrigerated) for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.