Description

Di-tert-Butyl (6-Amino-2-Methylpyrimidin-4-Yl)Carbamate is a high-purity, protected pyrimidine derivative that serves as a critical building block in advanced organic synthesis. This compound matters because it provides a versatile and reactive amino group, protected by a Boc (tert-butoxycarbonyl) group, enabling precise and efficient construction of complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs), intermediates, and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides that require specific pyrimidine-based scaffolds.
• Peptide Mimetics & Conjugates: Facilitates the introduction of pyrimidine motifs into peptide chains or bioconjugates for drug discovery.
• Material Science Research: Acts as a monomer or functionalizing agent in the synthesis of specialty polymers and organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	Di-tert-Butyl (6-Amino-2-Methylpyrimidin-4-Yl)Carbamate
CAS No.	1364663-30-8
Molecular Formula	C14H22N4O2
Molecular Weight	278.35 g/mol
Synonyms	Boc-Protected 6-Amino-2-methylpyrimidin-4-amine; Di-tert-butyl N-(6-amino-2-methylpyrimidin-4-yl)carbamate; 4-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-methyl-6-pyrimidinamine; 6-Amino-2-methylpyrimidin-4-yl-carbamic acid di-tert-butyl ester; (6-Amino-2-methylpyrimidin-4-yl)-carbamic acid bis(1,1-dimethylethyl) ester; N-Boc-6-amino-2-methylpyrimidin-4-amine; tert-Butyl (6-amino-2-methylpyrimidin-4-yl)carbamate (common misnomer); 1364663-30-8 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our Di-tert-Butyl (6-Amino-2-Methylpyrimidin-4-Yl)Carbamate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports applications requiring high standards, such as cGMP (current Good Manufacturing Practice) development and research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.