Description

5-Bromo-4-Fluoro-2-Methoxyphenol is a high-purity halogenated phenolic compound that serves as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and pesticides, leveraging its halogenated phenolic structure for bioactivity.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing substituents.
• Chemical Biology Probes: Serves as a core structure for creating fluorescent tags, photoaffinity labels, and other molecular probes for biochemical research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	5-Bromo-4-Fluoro-2-Methoxyphenol
CAS No.	1364606-67-6
Molecular Formula	C7H6BrFO2
Molecular Weight	221.03 g/mol
Synonyms	4-Fluoro-5-bromo-2-methoxyphenol; 2-Methoxy-5-bromo-4-fluorophenol; 5-Bromo-4-fluoro-2-methoxyphenol; 5-Bromo-4-fluoro-guaiacol; Phenol, 5-bromo-4-fluoro-2-methoxy-; 1364606-67-6
EINECS	Contact for details

Quality Control

Our production of 5-Bromo-4-Fluoro-2-Methoxyphenol adheres to stringent quality management protocols. Every batch is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR) to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our facilities operate under cGMP principles where applicable, ensuring traceability and reliability for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider maintaining under an inert atmosphere (e.g., nitrogen or argon) to preserve stability and prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.