Description

Methyl 7H-Pyrrolo[2,3-D]Pyrimidine-2-Carboxylate is a high-purity heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of novel pharmaceutical agents, particularly in kinase inhibitor research. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted small molecule drugs, especially kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel therapeutic candidates.
• Chemical Biology Probes: Serves as a scaffold for developing tool compounds to study biological pathways and protein function.
• Agrochemical Research: Potential intermediate in the discovery of new active ingredients for crop protection.
• Academic & Contract Research: Employed in university and CRO laboratories for exploratory synthetic chemistry and method development.

Basic Information

Product Name	Methyl 7H-Pyrrolo[2,3-D]Pyrimidine-2-Carboxylate
CAS No.	1363380-73-7
Molecular Formula	C8H7N3O2
Molecular Weight	177.16 g/mol
Synonyms	7H-Pyrrolo[2,3-d]pyrimidine-2-carboxylic acid, methyl ester; Methyl 7H-pyrrolo[2,3-d]pyrimidine-2-carboxylate; 2-Carbomethoxy-7H-pyrrolo[2,3-d]pyrimidine; Methyl pyrrolo[2,3-d]pyrimidine-2-carboxylate; Pyrrolopyrimidine-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 7H-Pyrrolo[2,3-D]Pyrimidine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/LC-MS for identity confirmation, to ensure it meets the stringent requirements of pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.