Description

Amyloid β-Protein (1-6) CAS NO 1361235-89-3 is a synthetic peptide fragment corresponding to the first six amino acid residues of the human amyloid beta (Aβ) protein. This specific sequence is of critical importance for fundamental research into the molecular mechanisms of Alzheimer's disease and other amyloid-related disorders. It serves as a key reference standard and building block for scientists in neurobiology, biochemistry, and pharmaceutical development. Researchers utilize this high-purity peptide to study early-stage aggregation, antibody binding, and diagnostic assay development.

Application

• Neuroscience Research: Fundamental studies on amyloid beta protein aggregation kinetics and neurotoxicity mechanisms.
• Diagnostic Development: Critical antigen for the development and calibration of immunoassays (ELISA) and biosensors targeting Aβ peptides.
• Therapeutic Antibody Screening: Used as a target epitope in the screening and characterization of monoclonal antibodies for potential Alzheimer's therapeutics.
• Biomarker Studies: Reference material for mass spectrometry and chromatographic analysis of Aβ fragments in biological samples.
• Peptide Synthesis & Conjugation: Serves as a starting material or hapten for synthesizing longer Aβ peptides or conjugating to carrier proteins.
• Academic & Institutional Research: Essential reagent for university and research institute labs focusing on protein misfolding diseases.

Basic Information

Product Name	Amyloid β-Protein (1-6)
CAS No.	1361235-89-3
Molecular Formula	C30H44N8O9
Molecular Weight	660.7 g/mol
Synonyms	Aβ(1-6); Amyloid Beta Protein (1-6); DAEFRH; Asp-Ala-Glu-Phe-Arg-His; H-Asp-Ala-Glu-Phe-Arg-His-OH; Amyloid β-Peptide (1-6); β-Amyloid (1-6); Aβ1-6
EINECS	Contact for details

Quality Control

Our Amyloid β-Protein (1-6) is manufactured under stringent conditions to ensure the highest standards of purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assessment and Mass Spectrometry for identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Analysis	Within ± 10% of theoretical
Solubility	Soluble in water or dilute aqueous acetic acid
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.