Description

n-(2-Furoyl)Leucine is a specialized amino acid derivative where a furoyl group is conjugated to the L-leucine backbone. This compound is significant for its role as a key synthetic intermediate and building block in advanced pharmaceutical research and peptide chemistry. It is primarily needed by R&D chemists and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic agents and bioactive molecules.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate modified leucine residues for structure-activity relationship (SAR) studies.
• Bioconjugation & Probe Development: Serves as a precursor for creating fluorescent probes, affinity labels, or other bioconjugates for biochemical research.
• Chemical Biology Research: Employed in the development of enzyme inhibitors, receptor ligands, and other bioactive tools to study biological pathways.
• Fine Chemical Synthesis: Acts as a chiral synthon for the asymmetric synthesis of complex organic molecules with high stereochemical purity.

Basic Information

Product Name	n-(2-Furoyl)Leucine
CAS No.	1361143-17-0
Molecular Formula	C11H15NO4
Molecular Weight	225.24 g/mol
Synonyms	N-(2-Furoyl)-L-leucine; L-Leucine, N-(2-furoyl)-; (S)-2-(Furan-2-carboxamido)-4-methylpentanoic acid; 2-Furoyl-L-leucine; Furoylleucine; Leucine, N-furoyl-; Furoic acid leucinamide derivative
EINECS	Contact for details

Quality Control

Our n-(2-Furoyl)Leucine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and residual solvent screening. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Chiral Purity (HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.