Description

4-Pyrrolidin-2-Yl-Pyrimidin-2-Ylamine Dihydrochloride is a high-purity, pharmaceutically relevant organic salt used as a critical building block in advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals, where precise molecular structure is paramount. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates, particularly in kinase inhibitor research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Chemical Biology Probes: Employed in the development of tool compounds for studying biological pathways and target validation.
• Process Chemistry Development: Utilized in scaling up synthetic routes from laboratory to pilot plant scale for API manufacturing.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, high-value fine chemicals.
• Academic Research: Used in university and institutional labs for exploratory synthetic organic chemistry projects.

Basic Information

Product Name	4-Pyrrolidin-2-Yl-Pyrimidin-2-Ylamine Dihydrochloride
CAS No.	1361114-23-9
Molecular Formula	C9H15Cl2N5
Molecular Weight	264.16 g/mol
Synonyms	2-Pyrimidinamine, 4-(2-pyrrolidinyl)-, dihydrochloride; 4-(Pyrrolidin-2-yl)pyrimidin-2-amine dihydrochloride; 4-(2-Pyrrolidinyl)-2-pyrimidinamine dihydrochloride; 4-(2-Aminopyrimidin-4-yl)pyrrolidine dihydrochloride; 4-(2-Pyrrolidinyl)pyrimidin-2-amine hydrochloride (1:2); CAS 1361114-23-9
EINECS	Contact for details

Quality Control

Our 4-Pyrrolidin-2-Yl-Pyrimidin-2-Ylamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.