Description

4-Piperidin-2-Yl-Pyrimidine Dihydrochloride is a high-purity organic salt of significant interest in advanced chemical synthesis. This compound serves as a critical pharmacophore and versatile building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by pharmaceutical R&D laboratories and contract manufacturing organizations (CMOs) engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly in therapeutic areas targeting the central nervous system.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying biological pathways and target validation.
• Process Chemistry & Scale-Up: Serves as a starting material for the optimization and commercial-scale production of active pharmaceutical ingredients (APIs).
• Fine Chemical Synthesis: Utilized in the preparation of specialized, high-value compounds for agrochemical and material science applications.

Basic Information

Product Name	4-Piperidin-2-Yl-Pyrimidine Dihydrochloride
CAS No.	1361112-28-8
Molecular Formula	C9H14N4·2HCl
Molecular Weight	263.16 g/mol
Synonyms	2-(Pyrimidin-4-yl)piperidine dihydrochloride; 4-(2-Piperidinyl)pyrimidine dihydrochloride; 4-(Piperidin-2-yl)pyrimidine hydrochloride (1:2); 4-(2-Piperidyl)pyrimidine dihydrochloride; 4-Piperidin-2-ylpyrimidine dihydrochloride; 4-(2-Piperidinyl)pyrimidine, 2HCl
EINECS	Contact for details

Quality Control

Our 4-Piperidin-2-Yl-Pyrimidine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency, meeting the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.