Description

2-(5-Borono-2-Pyrimidinyl)Imidodicarbonic Acid 1,3-Bis(tert-Butyl) Ester is a sophisticated boronic acid ester derivative, a key protected intermediate in modern synthetic chemistry. Its primary value lies in enabling complex cross-coupling reactions, particularly Suzuki-Miyaura couplings, which are fundamental for constructing biaryl and heteroaryl structures in advanced materials and pharmaceuticals. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries who require high-purity, protected building blocks for synthesizing complex molecules.

Application

• Pharmaceutical Intermediate: A critical protected building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing pyrimidine and imidodicarbonic acid motifs.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a key boronic ester component for palladium-catalyzed carbon-carbon bond formation, essential for creating complex biaryl and heteroaryl scaffolds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific heterocyclic architectures.
• Material Science Research: Employed in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where precise molecular structure is crucial.
• Chemical Biology & Proteomics: Can be utilized as a synthetic handle or probe in the development of enzyme inhibitors or activity-based protein profiling agents.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting methodological research in synthetic organic chemistry.

Basic Information

Product Name	2-(5-Borono-2-Pyrimidinyl)Imidodicarbonic Acid 1,3-Bis(tert-Butyl) Ester
CAS No.	1360950-40-8
Molecular Formula	C15H23BN4O5
Molecular Weight	350.18 g/mol
Synonyms	1,3-Di-tert-butyl 2-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-yl]imidodicarbonate; 2-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-yl)-1H-imidazole-1,3(2H)-dicarboxylic acid 1,3-bis(1,1-dimethylethyl) ester; 2-(5-Boronopyrimidin-2-yl)imidodicarbonic Acid Bis(tert-butyl) Ester; 2-(5-Borono-2-pyrimidinyl)-1H-imidazole-1,3(2H)-dicarboxylic acid 1,3-di-tert-butyl ester; tert-Butyl 2-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-yl)imidodicarbonate
EINECS	Contact for details

Quality Control

Our production of 2-(5-Borono-2-Pyrimidinyl)Imidodicarbonic Acid 1,3-Bis(tert-Butyl) Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. All materials are subjected to rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.