Description

Fmoc-(S)-2-Aminomethy-Pentanoic Acid CAS NO 1359757-38-2 is a high-purity, non-natural amino acid derivative featuring an Fmoc-protected amino group. This compound is a critical chiral building block for the solid-phase peptide synthesis (SPPS) of complex peptides and peptidomimetics. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, proteomics, and the development of therapeutic peptides.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key chiral intermediate for the automated synthesis of custom peptides.
• Pharmaceutical Research: Building block for novel peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Peptidomimetic Design: Incorporation into modified peptide structures to enhance stability, bioavailability, or receptor binding affinity.
• Bioconjugation: Used in the preparation of peptide-protein or peptide-small molecule conjugates for diagnostic and therapeutic applications.
• Chemical Biology Probes: Synthesis of labeled or tagged peptides for studying protein-protein interactions and cellular processes.
• Academic & Industrial R&D: Fundamental research in organic chemistry, medicinal chemistry, and biochemistry.

Basic Information

Product Name	Fmoc-(S)-2-Aminomethy-Pentanoic Acid
CAS No.	1359757-38-2
Molecular Formula	C₂₂H₂₅NO₄
Molecular Weight	367.44 g/mol
Synonyms	Fmoc-(S)-2-Aminomethylpentanoic Acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-2-aminomethylpentanoic Acid; Fmoc-Amp(2)-OH; Fmoc-L-2-Aminomethylpentanoic Acid; (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]aminomethyl]pentanoic Acid; N-α-Fmoc-L-2-aminomethylpentanoic acid; Fmoc-Amino-methyl-norvaline; Fmoc-L-Aminomethylnorvaline
EINECS	Contact for details

Quality Control

Our Fmoc-(S)-2-Aminomethy-Pentanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high chemical purity, correct stereochemistry, and consistent performance in peptide synthesis. Certificates of Analysis (COA) detailing purity (by HPLC), chiral purity, and other critical parameters are provided with every shipment to ensure full traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.