Description

2-Chloro-5-Pyrimidin-4-Yl-Benzoic Acid is a high-purity, heterocyclic benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular architecture, featuring both pyrimidine and chlorinated benzoic acid moieties, makes it an invaluable intermediate for constructing complex pharmacologically active molecules. This compound is primarily utilized by research institutions and pharmaceutical development companies engaged in the discovery of new therapeutic agents, particularly in oncology and antiviral research.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel small-molecule drugs, especially kinase inhibitors.
• Agrochemical Research: Used in the synthesis of advanced crop protection agents and herbicides.
• Material Science: Serves as a precursor for functionalized polymers and advanced organic electronic materials.
• Chemical Biology: Employed as a molecular probe or linker in proteomics and bioconjugation studies.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs for bespoke chemical synthesis projects.

Basic Information

Product Name	2-Chloro-5-Pyrimidin-4-Yl-Benzoic Acid
CAS No.	1359706-37-8
Molecular Formula	C11H7ClN2O2
Molecular Weight	234.64 g/mol
Synonyms	4-(6-Chloro-3-pyridazinyl)benzoic Acid; 2-Chloro-5-(pyrimidin-4-yl)benzoic Acid; Benzoic acid, 2-chloro-5-(4-pyrimidinyl)-; 1359706-37-8; 4-Pyrimidinecarboxylic acid, 2-chloro-5-(4-pyrimidinyl)- (Related); 2-Chloro-5-(4-pyrimidinyl)benzoic acid
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Pyrimidin-4-Yl-Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the stringent requirements of research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.