Description

N,n-Dimethyl-4-(Piperidin-3-Ylmethyl)Pyrimidin-2-Amine CAS NO 1359705-77-3 is a high-purity, advanced pharmaceutical intermediate featuring a unique pyrimidine-piperidine hybrid structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of investigational new drugs, especially those targeting central nervous system (CNS) disorders and other specialized therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities in drug discovery programs.
• Process Chemistry & Scale-Up: Used in the development and optimization of robust, scalable synthetic routes for API manufacturing under cGMP conditions.
• Biochemical Research: May be employed as a reference standard or a ligand in biochemical assays and pharmacological studies.
• Custom Synthesis: Acts as a starting material for the custom synthesis of more complex, proprietary molecules for client-specific applications.

Basic Information

Product Name	N,n-Dimethyl-4-(Piperidin-3-Ylmethyl)Pyrimidin-2-Amine
CAS No.	1359705-77-3
Molecular Formula	C12H20N4
Molecular Weight	220.32 g/mol
Synonyms	4-[(3-Piperidinyl)methyl]-N,N-dimethyl-2-pyrimidinamine; 2-Pyrimidinamine, N,N-dimethyl-4-[(3-piperidinyl)methyl]-; N,N-Dimethyl-4-(piperidin-3-ylmethyl)pyrimidin-2-amine; 1359705-77-3; 4-(Piperidin-3-ylmethyl)-N,N-dimethylpyrimidin-2-amine
EINECS	Contact for details

Quality Control

Our N,n-Dimethyl-4-(Piperidin-3-Ylmethyl)Pyrimidin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to ISO 9001 standards, and we support development under ICH Q7 guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.