Description

tert-Butyl 2-Chloro-5-Iodopyrimidin-4-Ylcarbamate is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in providing a versatile scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is critically needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Research: Used as a building block for developing novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology: Serves as a versatile probe or linker in the development of chemical tools and bioconjugates.
• Material Science: Potential monomer or precursor for creating functional polymers and advanced organic materials.
• Cross-Coupling Reactions: The iodine and chlorine substituents make it an excellent substrate for Suzuki, Sonogashira, and other palladium-catalyzed cross-coupling reactions.
• Nucleophilic Substitution: The chloro and carbamate groups provide sites for selective displacement with various nucleophiles to introduce diverse functionality.

Basic Information

Product Name	tert-Butyl 2-Chloro-5-Iodopyrimidin-4-Ylcarbamate
CAS No.	1359655-47-2
Molecular Formula	C9H11ClIN3O2
Molecular Weight	355.56 g/mol
Synonyms	4-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-chloro-5-iodopyrimidine; 2-Chloro-5-iodopyrimidin-4-amine, N-BOC-protected; tert-Butyl (2-chloro-5-iodopyrimidin-4-yl)carbamate; BOC-2-Chloro-5-iodopyrimidin-4-amine; 4-(Boc-amino)-2-chloro-5-iodopyrimidine; 2-Chloro-5-iodo-4-pyrimidinamine, N-BOC derivative; CAS 1359655-47-2
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Chloro-5-Iodopyrimidin-4-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee consistency and traceability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability. Keep the container sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.