Description

6-Oxo-1,6-Dihydropyridine-3-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in enabling the efficient introduction of the sulfonamide functional group, a key motif in modern medicinal chemistry and material science. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of sulfonamide-based drug candidates, including kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides with sulfonamide backbones.
• Material Science Research: Employed as a functionalization agent for creating advanced polymers, dyes, and liquid crystals with specific sulfonamide properties.
• Chemical Biology Probes: Acts as a reactive handle for labeling proteins or other biomolecules to study biological pathways and interactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring the introduction of a sulfonyl chloride moiety onto a pyridone scaffold.

Basic Information

Product Name	6-Oxo-1,6-Dihydropyridine-3-Sulfonyl Chloride
CAS No.	1357566-60-9
Molecular Formula	C5H4ClNO3S
Molecular Weight	193.61 g/mol
Synonyms	3-Pyridinesulfonyl chloride, 1,6-dihydro-6-oxo-; 1,6-Dihydro-6-oxo-3-pyridinesulfonyl chloride; 6-Hydroxypyridine-3-sulfonyl chloride; 6-Oxo-1,6-dihydropyridine-3-sulfonyl chloride; 3-Sulfonylchloride-6-hydroxypyridine; 6-Hydroxy-3-pyridinesulfonyl chloride; 1,2-Dihydropyridin-6-one-3-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 6-Oxo-1,6-Dihydropyridine-3-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our commitment to quality ensures reliable performance in your sensitive synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.