Description

3-Bromo-4-Fluoro-5-Iodobenzaldehyde, 97% is a high-purity, multi-halogenated aromatic aldehyde building block of significant synthetic utility. This compound is valued for its versatility as a key intermediate in advanced organic synthesis, particularly in the construction of complex molecules for pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications in cross-coupling reactions, medicinal chemistry, and ligand synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), especially in drug discovery programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Sonogashira couplings due to the presence of bromo and iodo substituents, enabling diverse carbon-carbon bond formations.
• Medicinal Chemistry & SAR Studies: Employed to introduce halogenated benzaldehyde motifs into lead compounds for structure-activity relationship (SAR) optimization.
• Ligand and Catalyst Development: Used to synthesize novel chelating ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Item	Details
Product Name	3-Bromo-4-Fluoro-5-Iodobenzaldehyde, 97%
CAS No.	1356113-37-5
Molecular Formula	C7H3BrFIO
Molecular Weight	328.91 g/mol
Synonyms	3-Bromo-4-fluoro-5-iodobenzaldehyde; 5-Iodo-3-bromo-4-fluorobenzaldehyde; Benzaldehyde, 3-bromo-4-fluoro-5-iodo-; (3-Bromo-4-fluoro-5-iodophenyl)methanal; 1356113-37-5; BFD-3-Bromo-4-Fluoro-5-Iodobenzaldehyde
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Fluoro-5-Iodobenzaldehyde, 97% is manufactured under strict quality control protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.