Description

4-Bromo-3-Fluoro-5-Methylaniline is a high-purity halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which allows for selective functionalization and the introduction of specific steric and electronic properties into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules requiring halogenated aromatic motifs for bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, where the bromo and fluoro substituents can enhance potency and environmental selectivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials due to its aromatic amine functionality.
• Dye and Pigment Intermediate: Acts as a building block for synthesizing complex dyes and pigments with specific color and fastness properties.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions to construct biaryl and other complex structures.

Basic Information

Product Name	4-Bromo-3-Fluoro-5-Methylaniline
CAS No.	1356113-07-9
Molecular Formula	C7H7BrFN
Molecular Weight	204.04 g/mol
Synonyms	3-Fluoro-5-methyl-4-bromoaniline; 4-Bromo-3-fluoro-5-methylbenzenamine; 5-Amino-2-bromo-1-fluoro-3-methylbenzene; 2-Bromo-6-fluoro-4-aminotoluene; Benzenamine, 4-bromo-3-fluoro-5-methyl-; 4-Bromo-3-fluoro-5-methyl-phenylamine
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Fluoro-5-Methylaniline is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the stringent requirements for research and cGMP manufacturing applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.