Description

2-Chlorothieno[3,2-D]Pyrimidine-7-Carboxylic Acid is a high-value heterocyclic building block and key synthetic intermediate. Its fused thienopyrimidine scaffold with a carboxylic acid functional group makes it a versatile precursor for constructing complex molecular architectures. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of kinase inhibitors, anticancer agents, and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its heterocyclic core for bioactivity.
• Material Science Precursor: Serves as a starting material for creating advanced organic electronic materials, such as organic semiconductors or light-emitting compounds.
• Chemical Biology Probe Synthesis: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A key substrate for custom chemical synthesis services catering to R&D and pre-clinical development projects.
• Academic & Institutional Research: Utilized in universities and research institutes for methodological development and exploring new chemical reactions.

Basic Information

Product Name	2-Chlorothieno[3,2-D]Pyrimidine-7-Carboxylic Acid
CAS No.	1356016-36-8
Molecular Formula	C7H3ClN2O2S
Molecular Weight	214.63 g/mol
Synonyms	2-Chlorothieno[3,2-d]pyrimidine-7-carboxylic acid; 7-Carboxy-2-chlorothieno[3,2-d]pyrimidine; Thieno[3,2-d]pyrimidine-7-carboxylic acid, 2-chloro-; 2-Chloro-7-thieno[3,2-d]pyrimidinecarboxylic Acid; 2-Chloro-thieno[3,2-d]pyrimidine-7-carboxylic acid; 1356016-36-8; 2-Chloro-7-carboxythieno[3,2-d]pyrimidine
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fine chemical intermediates. Production follows cGMP principles where applicable, and each batch is analyzed to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing key parameters such as assay (HPLC), related substances, and residual solvents. Our quality system is designed to meet the exacting standards of pharmaceutical and advanced material research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.