Description

3-Cyclohexyl-D-Alanyl-D-α-Glutamylglycine-D11 is a high-purity, deuterated peptide derivative designed for advanced research and development applications. This compound serves as a critical building block and analytical standard in pharmaceutical and biochemical research, offering enhanced stability and traceability due to its deuterium labeling. It is primarily utilized by research scientists and process development teams in the pharmaceutical, biotechnology, and academic sectors for applications in drug discovery, metabolic studies, and proteomics.

Application

• Pharmaceutical Reference Standard: Used as a certified internal standard for the precise quantification of peptides and related compounds in bioanalytical methods like LC-MS/MS.
• Drug Discovery & Development: Acts as a key intermediate or a stable isotope-labeled analog in the synthesis and metabolic pathway investigation of novel therapeutic peptides.
• Proteomics Research: Employed in mass spectrometry-based studies for protein identification, quantification, and post-translational modification analysis.
• Metabolic Tracing: Utilized in pharmacokinetic and pharmacodynamic studies to track the absorption, distribution, metabolism, and excretion (ADME) of peptide-based drug candidates.
• Biochemical Reagent: Serves as a substrate or inhibitor in enzymatic assays to study protease activity and enzyme kinetics.
• Academic Research: Supports fundamental research in peptide chemistry, structural biology, and molecular modeling.

Basic Information

Item	Detail
Product Name	3-Cyclohexyl-D-Alanyl-D-α-Glutamylglycine-D11
CAS No.	1356011-66-9
Molecular Formula	C16H16D11N3O5
Molecular Weight	Contact for details
Synonyms	Cyclohexyl-D-Ala-D-Glu-Gly-D11; Deuterated CAGE Tripeptide; D11-Labeled 3-Cyclohexyl-DADG; (2R)-2-[[(2R)-2-[[(2R)-2-Amino-3-cyclohexylpropanoyl]amino]-4-carboxybutanoyl]amino]acetic-2,2-d2 acid-1,1,1,2,2,3,3,4,4,5,5-undecadeuterio; 3-Cyclohexyl-D-Ala-D-Glu-Gly-D11; Perdeuterated Glycine Peptide Derivative; DADG-D11; Research Peptide Standard D11
EINECS	Contact for details

Quality Control

Every batch of 3-Cyclohexyl-D-Alanyl-D-α-Glutamylglycine-D11 is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and isotopic enrichment. Our quality assurance protocol is designed to meet the exacting standards of research and development. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), isotopic purity (by MS), and other critical parameters is provided with each shipment to guarantee traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a desiccated environment to maintain stability and prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Isotopic Purity (D11)	≥ 98.0 atom % D
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.