Description

2-(4-Amino-3-Fluorophenyl)-1,1,1,3,3,3-Hexafluoropropan-2-Ol is a high-value fluorinated aromatic building block, distinguished by its unique combination of an amino group and a hexafluoroisopropanol moiety. This compound is critical for advanced organic synthesis, enabling the introduction of fluorine atoms to enhance the metabolic stability, lipophilicity, and bioavailability of target molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in oncology, CNS, and antiviral research.
• Agrochemical Synthesis: Used in the design and production of advanced herbicides, fungicides, and insecticides with improved environmental and efficacy profiles.
• Liquid Crystal Materials: Serves as a precursor for fluorinated components in electronic display technologies.
• Polymer Modification: Imparts unique properties like chemical resistance and low surface energy when incorporated into specialty polymers.
• Advanced Material Science: Employed in the synthesis of complex organic frameworks and functional materials.
• Chemical Research & Development: A versatile reagent for exploring new fluorination methodologies and creating novel chemical entities in academic and industrial labs.

Basic Information

Product Name	2-(4-Amino-3-Fluorophenyl)-1,1,1,3,3,3-Hexafluoropropan-2-Ol
CAS No.	1355338-16-7
Molecular Formula	C9H5F7NO
Molecular Weight	267.13 g/mol
Synonyms	3-Fluoro-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)aniline; 4-Amino-3-fluoro-α-(trifluoromethyl)benzenemethanol, hexafluoro deriv.; 2-(4-Amino-3-fluorophenyl)hexafluoroisopropanol; 1,1,1,3,3,3-Hexafluoro-2-(4-amino-3-fluorophenyl)propan-2-ol; 4-(1,1,1,3,3,3-Hexafluoro-2-hydroxy-2-propyl)-2-fluoroaniline; 2-(4-Amino-3-fluorophenyl)-1,1,1,3,3,3-hexafluoro-2-propanol; HFIP-Aniline-F derivative
EINECS	Contact for details

Quality Control

Our production of 2-(4-Amino-3-Fluorophenyl)-1,1,1,3,3,3-Hexafluoropropan-2-Ol adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. The container must be kept tightly sealed due to the compound's sensitivity to moisture and light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.