Description

3-(3,5-Difluorophenyl)Aniline, Hcl is a high-purity, halogenated aniline derivative supplied as its hydrochloride salt. This compound is a critical pharmaceutical intermediate and versatile organic building block for advanced synthesis. It is primarily utilized by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and pesticides, leveraging the difluorophenyl moiety for enhanced bioactivity and stability.
• Ligand & Catalyst Development: Used in organometallic chemistry to create novel ligands for catalysis and material science applications.
• Fluorescent Dye & Sensor Chemistry: Serves as a core structure in the synthesis of advanced organic dyes and molecular sensors.
• Polymer & Material Science: Monomer or additive for creating specialty polymers with specific thermal or chemical resistance properties.
• Research & Development: Essential compound for medicinal chemistry programs and structure-activity relationship (SAR) studies in academic and industrial labs.

Basic Information

Product Name	3-(3,5-Difluorophenyl)Aniline, Hcl
CAS No.	1355247-52-7
Molecular Formula	C12H9ClF2N
Molecular Weight	240.66 g/mol
Synonyms	3-(3,5-Difluorophenyl)aniline hydrochloride; 3-Amino-3',5'-difluorobiphenyl hydrochloride; Benzenamine, 3-(3,5-difluorophenyl)-, hydrochloride; 3-(3,5-Difluorophenyl)phenylamine HCl; 3,5-Difluoro-3'-aminobiphenyl hydrochloride; 3-(3,5-Difluorophenyl)benzenamine hydrochloride
EINECS	Contact for details

Quality Control

Our 3-(3,5-Difluorophenyl)Aniline, Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring GMP-grade intermediates and research materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.