Description

Fmoc-S-Carbamoyl-L-Cysteine is a specialized, protected amino acid derivative used in solid-phase peptide synthesis (SPPS). This compound is critical for the controlled introduction of cysteine residues with a protected thiol group, enabling the synthesis of complex peptides and proteins. It is an essential building block for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors developing therapeutic peptides, diagnostic tools, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected intermediate for the controlled incorporation of cysteine into peptide chains.
• Therapeutic Peptide Development: Used in the research and production of peptide-based drugs targeting various diseases.
• Protein Engineering: Facilitates site-specific modifications and the study of protein structure-function relationships.
• Bioconjugation: Serves as a precursor for creating peptide-based conjugates for drug delivery and diagnostics.
• Chemical Biology Research: Enables the synthesis of custom peptides for probing biological mechanisms and interactions.
• Antibody-Drug Conjugate (ADC) Linker Chemistry: Potential use in constructing specialized linkers for targeted cancer therapies.

Basic Information

Product Name	Fmoc-S-Carbamoyl-L-Cysteine
CAS No.	1354488-29-1
Molecular Formula	C19H18N2O6S
Molecular Weight	402.42 g/mol
Synonyms	Fmoc-Cys(Cam)-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-S-carbamoyl-L-cysteine; Fmoc-L-Cysteine(S-carbamoyl); (2R)-2-[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-3-[(aminocarbonyl)thio]propanoic acid; Fmoc-Cys(CONH2)-OH; Fmoc-S-Carbamoylcysteine; Nα-Fmoc-S-carbamoyl-L-cysteine
EINECS	Contact for details

Quality Control

Our Fmoc-S-Carbamoyl-L-Cysteine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and cGMP-grade material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.