Description

Boc-S-Carboxymethyl-L-Cysteine is a protected derivative of the amino acid L-cysteine, featuring a tert-butoxycarbonyl (Boc) group on the amine and a carboxymethyl moiety on the sulfur. This compound is a crucial building block in peptide synthesis and chemical research, offering enhanced stability and controlled reactivity for the selective formation of disulfide bonds and other sulfur-based modifications. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries for developing novel therapeutic peptides, protein conjugates, and advanced biomaterials.

Application

• Peptide Synthesis: A key protected intermediate for the solid-phase and solution-phase synthesis of complex peptides containing cysteine residues.
• Bioconjugation: Used to introduce thiol-reactive handles for site-specific labeling of proteins, antibodies, and other biomolecules.
• Drug Discovery: Serves as a critical scaffold in medicinal chemistry for developing peptide-based drugs targeting various diseases.
• Linker Chemistry: The carboxymethyl group provides a carboxylic acid functionality for coupling to amines, enabling its use as a versatile heterobifunctional linker.
• Biomaterial Functionalization: Employed to modify surfaces and polymers with thiol-reactive groups for creating bioactive materials.
• Research & Development: Essential for academic and industrial R&D exploring disulfide bond formation, protein folding, and redox biology.

Basic Information

Product Name	Boc-S-Carboxymethyl-L-Cysteine
CAS No.	1354485-84-9
Molecular Formula	C10H17NO6S
Molecular Weight	279.31 g/mol
Synonyms	(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-((carboxymethyl)thio)propanoic acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-S-carboxymethyl-L-cysteine; Fmoc-Cys(CH2COOH)-OH; Fmoc-S-Carboxymethyl-L-cysteine; N-α-Fmoc-S-carboxymethyl-L-cysteine; N-Fmoc-S-(carboxymethyl)-L-cysteine; S-Carboxymethyl-N-Fmoc-L-cysteine; L-Cysteine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-S-(carboxymethyl)-
EINECS	Contact for details

Quality Control

Our Boc-S-Carboxymethyl-L-Cysteine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.