Description

(R)-1-(6-Ethoxy-2-Methylsulfanyl-Pyrimidin-4-Yl)-Pyrrolidin-3-Ol is a high-purity chiral building block and pharmaceutical intermediate of significant importance in modern synthetic chemistry. This compound matters for its role in the development of enantiomerically pure active pharmaceutical ingredients (APIs), where stereochemical control is critical for efficacy and safety. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the synthesis of novel therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Asymmetric Synthesis: Used as a precursor or ligand in catalytic asymmetric reactions to construct complex molecules with high enantiomeric excess.
• Agrochemical Research: Serves as a building block for developing novel, enantiopure pesticides and herbicides with improved selectivity.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and enzyme inhibitors for target validation studies.
• Material Science: Potential use in the synthesis of advanced organic materials and liquid crystals where specific molecular chirality is required.
• Contract Research & Manufacturing (CRMO): Supplied to service organizations for custom synthesis projects and scale-up development.

Basic Information

Product Name	(R)-1-(6-Ethoxy-2-Methylsulfanyl-Pyrimidin-4-Yl)-Pyrrolidin-3-Ol
CAS No.	1354019-51-4
Molecular Formula	C11H17N3O2S
Molecular Weight	255.34 g/mol
Synonyms	(R)-1-(6-Ethoxy-2-(Methylthio)pyrimidin-4-yl)pyrrolidin-3-ol; (3R)-1-[6-Ethoxy-2-(methylsulfanyl)pyrimidin-4-yl]pyrrolidin-3-ol; (R)-3-Hydroxy-1-(6-ethoxy-2-(methylthio)pyrimidin-4-yl)pyrrolidine; 1354019-51-4; Pyrrolidin-3-ol, 1-(6-ethoxy-2-(methylthio)-4-pyrimidinyl)-, (3R)-; (R)-1-(6-Ethoxy-2-(methylmercapto)pyrimidin-4-yl)pyrrolidin-3-ol
EINECS	Contact for details

Quality Control

Our (R)-1-(6-Ethoxy-2-Methylsulfanyl-Pyrimidin-4-Yl)-Pyrrolidin-3-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.