Description

3-(6-Methoxy-2-Methylsulfanyl-Pyrimidin-4-Ylamino)-Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester is a sophisticated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical agents, particularly in medicinal chemistry programs targeting specific biological pathways. Pharmaceutical R&D teams and fine chemical manufacturers need this high-purity intermediate to streamline the synthesis of complex molecules, ensuring process efficiency and structural integrity.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly in kinase inhibitor research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel therapeutic agents.
• Custom Synthesis: Serves as a starting material or advanced intermediate for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds.
• Chemical Biology Probes: Utilized in the development of chemical probes for studying enzyme function and cellular signaling pathways.
• Agrochemical Research: Potential intermediate in the discovery and development of new crop protection agents and pesticides.

Basic Information

Product Name	3-(6-Methoxy-2-Methylsulfanyl-Pyrimidin-4-Ylamino)-Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1353987-53-7
Molecular Formula	C15H24N4O3S
Molecular Weight	340.44 g/mol
Synonyms	tert-Butyl 3-[(6-methoxy-2-methylsulfanylpyrimidin-4-yl)amino]pyrrolidine-1-carboxylate; 1-Boc-3-[(6-methoxy-2-(methylthio)pyrimidin-4-yl)amino]pyrrolidine; 3-[(6-Methoxy-2-(methylthio)pyrimidin-4-yl)amino]-1-pyrrolidinecarboxylic Acid 1,1-Dimethylethyl Ester; 1-(tert-Butoxycarbonyl)-3-[(6-methoxy-2-(methylthio)pyrimidin-4-yl)amino]pyrrolidine; BOC-3-(6-Methoxy-2-Methylsulfanyl-Pyrimidin-4-Ylamino)-Pyrrolidine
EINECS	Contact for details

Quality Control

Our production of 3-(6-Methoxy-2-Methylsulfanyl-Pyrimidin-4-Ylamino)-Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester adheres to stringent quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All materials undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.