Description

[6-(3-Aminomethyl-Piperidin-1-Yl)-Pyrimidin-4-Yl]-Cyclopropyl-Amine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the research and development of novel therapeutic agents, particularly in the field of kinase inhibition. It is primarily utilized by pharmaceutical R&D departments and fine chemical manufacturers engaged in the synthesis of targeted small molecule drugs. The product is supplied as a hydrochloride salt to enhance its stability and handling properties.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of investigational kinase inhibitors for oncology and inflammatory diseases.
• Chemical Biology Research: Used as a probe or precursor in biochemical assays to study enzyme function and signal transduction pathways.
• Preclinical Development: Serves as a critical starting material for producing candidate drug compounds for pharmacological and toxicological evaluation.
• Custom Synthesis: A versatile scaffold for medicinal chemists to create novel compound libraries for high-throughput screening.
• Academic Research: Employed in university and institutional labs for fundamental research in medicinal chemistry and drug discovery.
• Process Chemistry: Used in the development and scale-up of optimized synthetic routes for active pharmaceutical ingredients (APIs).

Basic Information

Item	Details
Product Name	[6-(3-Aminomethyl-Piperidin-1-Yl)-Pyrimidin-4-Yl]-Cyclopropyl-Amine Hydrochloride
CAS No.	1353985-14-4
Molecular Formula	C14H24ClN5
Molecular Weight	297.83 g/mol
Synonyms	Cyclopropyl-[6-(3-piperidinylmethylamino)pyrimidin-4-yl]amine hydrochloride; 1-Piperidinemethanamine, N-[(6-[(cyclopropylamino)-4-pyrimidinyl]methyl]-, hydrochloride; 1353985-14-4; 6-(3-Aminomethylpiperidin-1-yl)-N-cyclopropylpyrimidin-4-amine hydrochloride; UNII-9J8F8Y6F8Q; 9J8F8Y6F8Q; AKOS025147024; CS-0446647
EINECS	Contact for details

Quality Control

Every batch of [6-(3-Aminomethyl-Piperidin-1-Yl)-Pyrimidin-4-Yl]-Cyclopropyl-Amine Hydrochloride is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.