Description

1-(4-Chloro-6-Methyl-Pyrimidin-2-Yl)-Piperidin-4-Ol is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrimidine-piperidine hybrid structure. This compound is of significant commercial importance for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of novel drug candidates, particularly in kinase inhibitor programs.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging its heterocyclic core.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the scaled-up production of target molecules for preclinical and clinical trials.

Basic Information

Product Name	1-(4-Chloro-6-Methyl-Pyrimidin-2-Yl)-Piperidin-4-Ol
CAS No.	1353984-94-7
Molecular Formula	C10H14ClN3O
Molecular Weight	227.69 g/mol
Synonyms	4-Piperidinol, 1-(4-chloro-6-methyl-2-pyrimidinyl)-; 1-(4-Chloro-6-methylpyrimidin-2-yl)piperidin-4-ol; 4-Hydroxy-1-(4-chloro-6-methylpyrimidin-2-yl)piperidine; 2-(4-Hydroxypiperidin-1-yl)-4-chloro-6-methylpyrimidine; C10H14ClN3O; 1353984-94-7
EINECS	Contact for details

Quality Control

Our 1-(4-Chloro-6-Methyl-Pyrimidin-2-Yl)-Piperidin-4-Ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.