Description

4-Ethoxy-6-(3-Methyl-Piperazin-1-Yl)-Pyrimidine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a defined molecular structure. This compound is critical for the research and development of novel therapeutic agents, particularly in the field of kinase inhibitors. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of complex active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of targeted kinase inhibitors for oncology and other therapeutic areas.
• Chemical Research: Used in academic and industrial laboratories for structure-activity relationship (SAR) studies and medicinal chemistry programs.
• Process Development: Serves as a critical starting material or intermediate in the scale-up and optimization of API manufacturing processes.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Custom Synthesis: Basis for the preparation of more complex, proprietary derivatives for drug discovery pipelines.

Basic Information

Product Name	4-Ethoxy-6-(3-Methyl-Piperazin-1-Yl)-Pyrimidine Hydrochloride
CAS No.	1353984-88-9
Molecular Formula	C11H19N5O·HCl
Molecular Weight	273.76 g/mol (free base)
Synonyms	4-Ethoxy-6-(3-methylpiperazin-1-yl)pyrimidine hydrochloride; 6-(3-Methyl-1-piperazinyl)-4-ethoxypyrimidine hydrochloride; 4-Ethoxy-6-(3-methyl-1-piperazinyl)pyrimidine HCl; 4-Ethoxy-6-(3-methylpiperazin-1-yl)pyrimidine HCl; 1353984-88-9; 4-Ethoxy-6-(3-methylpiperazin-1-yl)pyrimidine monohydrochloride
EINECS	Contact for details

Quality Control

Our 4-Ethoxy-6-(3-Methyl-Piperazin-1-Yl)-Pyrimidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.