Description

1-(6-Methoxy-Pyrimidin-4-Yl)-Pyrrolidin-3-Ol is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key chiral intermediate for constructing complex molecules with specific biological activity. Pharmaceutical research and development teams need it for the discovery and synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the research and development of new drug candidates, especially for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of advanced crop protection agents and pesticides, leveraging its pyrimidine core structure.
• Chemical Research & Development: Serves as a versatile building block in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Ligand and Catalyst Preparation: Utilized in the synthesis of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	1-(6-Methoxy-Pyrimidin-4-Yl)-Pyrrolidin-3-Ol
CAS No.	1353984-40-3
Molecular Formula	C9H13N3O2
Molecular Weight	195.22 g/mol
Synonyms	3-Pyrrolidinol, 1-(6-methoxy-4-pyrimidinyl)-; 1-(6-Methoxypyrimidin-4-yl)pyrrolidin-3-ol; Pyrrolidin-3-ol, 1-(6-methoxy-4-pyrimidinyl)-; 1353984-40-3; 1-(6-Methoxy-4-pyrimidinyl)-3-pyrrolidinol; 1-(6-Methoxypyrimidin-4-yl)-3-pyrrolidinol
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized and controlled using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as chiral purity, chemical purity, and residual solvents are available upon request. We adhere to cGMP guidelines for the manufacture of pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere if specified. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.