Description

3-[(6-Methoxy-2-Methylsulfanyl-Pyrimidin-4-Yl)-Methyl-Amino]-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a piperidine core protected by a Boc (tert-butoxycarbonyl) group. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel drug candidates targeting central nervous system and other therapeutic areas. It is primarily utilized by pharmaceutical R&D laboratories, custom synthesis providers, and manufacturers of active pharmaceutical ingredients (APIs) requiring sophisticated, multi-functional building blocks.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those containing piperidine and pyrimidine pharmacophores.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies for new therapeutic agents.
• Custom Synthesis: Serves as a starting material or intermediate for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds.
• Protease Inhibitor Development: The structural motifs suggest potential application in the development of protease or kinase inhibitors.
• Chemical Biology Probes: Can be utilized to create molecular probes for studying biological pathways and target engagement.

Basic Information

Item	Details
Product Name	3-[(6-Methoxy-2-Methylsulfanyl-Pyrimidin-4-Yl)-Methyl-Amino]-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1353981-37-9
Molecular Formula	C17H28N4O3S
Molecular Weight	368.49 g/mol
Synonyms	1-Boc-3-[(6-Methoxy-2-(methylthio)pyrimidin-4-yl)(methyl)amino]piperidine; tert-Butyl 3-[(6-methoxy-2-(methylsulfanyl)pyrimidin-4-yl)-methyl-amino]piperidine-1-carboxylate; 3-[(6-Methoxy-2-(methylthio)-4-pyrimidinyl)methylamino]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 1,1-Dimethylethyl 3-[[6-methoxy-2-(methylthio)-4-pyrimidinyl]methylamino]-1-piperidinecarboxylate; 3-[(6-Methoxy-2-methylsulfanylpyrimidin-4-yl)-methyl-amino]piperidine-1-carboxylic acid tert-butyl ester; Boc-3-((6-methoxy-2-(methylthio)pyrimidin-4-yl)(methyl)amino)piperidine
EINECS	Contact for details

Quality Control

Our 3-[(6-Methoxy-2-Methylsulfanyl-Pyrimidin-4-Yl)-Methyl-Amino]-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which can affect stability and handling. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.