Description

3-(6-Cyclopropylamino-Pyrimidin-4-Ylamino)-Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester is a sophisticated, high-purity chemical building block designed for advanced research and development. This compound is critical for medicinal chemistry programs, serving as a key intermediate in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D teams, agrochemical innovators, and contract research organizations (CROs) focused on developing new therapeutic agents and crop protection solutions.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of kinase inhibitors and other targeted small-molecule therapeutics.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new drug candidates.
• Agrochemical Development: Serves as a precursor in the research and synthesis of novel crop protection agents.
• Contract Manufacturing (CMO): Supplied to custom synthesis partners for the production of advanced intermediates under cGMP conditions.
• Academic & Institutional Research: Employed in chemical biology and drug discovery projects within university and government laboratories.
• Process Chemistry: Used in route scouting and scale-up development for new chemical entities (NCEs).

Basic Information

Product Name	3-(6-Cyclopropylamino-Pyrimidin-4-Ylamino)-Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1353980-52-5
Molecular Formula	C16H24N6O2
Molecular Weight	332.40 g/mol
Synonyms	tert-Butyl 3-[(6-(cyclopropylamino)pyrimidin-4-yl)amino]pyrrolidine-1-carboxylate; 1-Boc-3-[(6-(cyclopropylamino)pyrimidin-4-yl)amino]pyrrolidine; 3-[(6-(Cyclopropylamino)-4-pyrimidinyl]amino]-1-pyrrolidinecarboxylic Acid 1,1-Dimethylethyl Ester; 1,1-Dimethylethyl 3-[[6-(cyclopropylamino)-4-pyrimidinyl]amino]-1-pyrrolidinecarboxylate; 3-(6-Cyclopropylamino-pyrimidin-4-ylamino)-pyrrolidine-1-carboxylic acid tert-butyl ester; CAS 1353980-52-5
EINECS	Contact for details

Quality Control

Our 3-(6-Cyclopropylamino-Pyrimidin-4-Ylamino)-Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.