Description

[1-(6-Methoxy-2-Methylsulfanyl-Pyrimidin-4-Yl)-Piperidin-4-Yl]-Methyl-Carbamic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its specific pyrimidine-piperidine scaffold. This compound matters for its critical role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular structures. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities for drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its modifiable functional groups.
• Process Development: Serves as a critical intermediate in scaling up synthetic routes from laboratory to pilot plant and commercial production.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development services for the global pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.
• Pre-clinical Development: Integral component in producing compounds for pharmacological profiling, toxicology studies, and formulation development.

Basic Information

Product Name	[1-(6-Methoxy-2-Methylsulfanyl-Pyrimidin-4-Yl)-Piperidin-4-Yl]-Methyl-Carbamic Acid tert-Butyl Ester
CAS No.	1353980-23-0
Molecular Formula	C18H28N4O3S
Molecular Weight	380.50 g/mol
Synonyms	tert-Butyl N-methyl-N-[1-(6-methoxy-2-methylsulfanylpyrimidin-4-yl)piperidin-4-yl]carbamate; 4-[[(1,1-Dimethylethoxy)carbonyl](methyl)amino]-1-(6-methoxy-2-(methylthio)-4-pyrimidinyl)piperidine; BOC-Protected Aminopyrimidine Intermediate; 1-(6-Methoxy-2-(Methylthio)pyrimidin-4-yl)-4-[(methylcarbamoyl)oxy]piperidine tert-Butyl Ester; 1353980-23-0; UNII-Not Assigned
EINECS	Contact for details

Quality Control

Our [1-(6-Methoxy-2-Methylsulfanyl-Pyrimidin-4-Yl)-Piperidin-4-Yl]-Methyl-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D and cGMP starting material applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.