Description

(6-Methoxy-Pyrimidin-4-Yl)-Pyrrolidin-2-Ylmethyl-Amine Hydrochloride is a high-purity pharmaceutical intermediate and building block with the CAS registry number 1353980-10-5. This compound is valued for its role as a key synthetic precursor in the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic chemistry. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing complex pyrimidine and pyrrolidine-containing molecular architectures.
• Agrochemical Development: Serves as a precursor in the research and synthesis of new-generation pesticides and herbicides.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target validation.
• Process Chemistry & Scale-Up: Supports route scouting, optimization, and cGMP manufacturing for clinical trial material.

Basic Information

Product Name	(6-Methoxy-Pyrimidin-4-Yl)-Pyrrolidin-2-Ylmethyl-Amine Hydrochloride
CAS No.	1353980-10-5
Molecular Formula	C10H17ClN4O
Molecular Weight	244.72 g/mol
Synonyms	4-[(2-Pyrrolidinylmethyl)amino]-6-methoxypyrimidine hydrochloride; 6-Methoxy-4-[(2-pyrrolidinylmethyl)amino]pyrimidine hydrochloride; 4-[(Pyrrolidin-2-ylmethyl)amino]-6-methoxypyrimidine HCl; (6-Methoxypyrimidin-4-yl)(pyrrolidin-2-ylmethyl)amine hydrochloride; Pyrrolidin-2-ylmethyl-(6-methoxy-pyrimidin-4-yl)-amine hydrochloride; 1353980-10-5; UNII-6U2F4F7Q8H
EINECS	Contact for details

Quality Control

Our (6-Methoxy-Pyrimidin-4-Yl)-Pyrrolidin-2-Ylmethyl-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent control of residual solvents and impurities. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.