Description

[1-(6-Methoxy-2-Methylsulfanyl-Pyrimidin-4-Yl)-Piperidin-3-Yl]-Methyl-Carbamic Acid tert-Butyl Ester is a sophisticated piperidine-pyrimidine derivative, a key synthetic intermediate in modern pharmaceutical research and development. This compound is valued for its role in constructing complex molecular architectures, particularly in the synthesis of targeted therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel drug candidates.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new therapeutic molecules.
• Chemical Biology Probes: Serves as a precursor for developing molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke, multi-step synthetic routes for clients.
• Library Synthesis: A valuable scaffold for generating diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	[1-(6-Methoxy-2-Methylsulfanyl-Pyrimidin-4-Yl)-Piperidin-3-Yl]-Methyl-Carbamic Acid tert-Butyl Ester
CAS No.	1353966-92-3
Molecular Formula	C₁₇H₂₈N₄O₃S
Molecular Weight	368.49 g/mol
Synonyms	tert-Butyl N-methyl-N-[1-(6-methoxy-2-methylsulfanylpyrimidin-4-yl)piperidin-3-yl]carbamate; 1-(6-Methoxy-2-(methylthio)pyrimidin-4-yl)-N-methyl-N-(piperidin-3-yl)carbamic acid tert-butyl ester; BOC-protected piperidine-pyrimidine intermediate; 3-[[(1,1-Dimethylethoxy)carbonyl](methyl)amino]-1-[6-methoxy-2-(methylthio)-4-pyrimidinyl]piperidine; N-BOC-N-Methyl-1-(6-methoxy-2-(methylthio)pyrimidin-4-yl)piperidin-3-amine
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical characterization using techniques including HPLC, NMR, and MS to ensure structural identity and high chemical purity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment. We support development projects requiring material produced under GMP-like conditions for non-clinical studies.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability. Keep the container sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.