Description

4-(6-Ethoxy-2-Methylsulfanyl-Pyrimidin-4-Ylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a versatile building block for creating novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new drug candidates, particularly in areas requiring sophisticated heterocyclic and piperidine-based scaffolds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in R&D for structure-activity relationship (SAR) studies and lead optimization.
• Heterocyclic Compound Synthesis: Serves as a precursor for creating complex pyrimidine and piperidine-containing molecules.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule development.
• Library Synthesis: Useful for generating diverse compound libraries for high-throughput screening in drug discovery.
• Process Chemistry Development: Aids in scaling up synthetic routes from laboratory to pilot and commercial production scales.

Basic Information

Product Name	4-(6-Ethoxy-2-Methylsulfanyl-Pyrimidin-4-Ylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1353966-83-2
Molecular Formula	C18H28N4O3S
Molecular Weight	380.50 g/mol
Synonyms	4-[(6-Ethoxy-2-methylsulfanylpyrimidin-4-yl)amino]piperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-((6-ethoxy-2-(methylthio)pyrimidin-4-yl)amino)piperidine-1-carboxylate; 1-Boc-4-((6-ethoxy-2-(methylthio)pyrimidin-4-yl)amino)piperidine; 4-(6-Ethoxy-2-(methylthio)pyrimidin-4-ylamino)piperidine-1-carboxylic acid tert-butyl ester; 1353966-83-2; BOC-piperidine-pyrimidine intermediate
EINECS	Contact for details

Quality Control

Our 4-(6-Ethoxy-2-Methylsulfanyl-Pyrimidin-4-Ylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.