Description

[1-(6-Methoxy-Pyrimidin-4-Yl)-Piperidin-3-Yl]-Methyl-Carbamic Acid tert-Butyl Ester CAS NO 1353966-51-4 is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of critical importance for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new drugs, where consistent quality and reliable supply are paramount.

Application

This specialized intermediate serves as a crucial component in sophisticated chemical synthesis pathways. Its primary applications include:

• Pharmaceutical Intermediate: A key precursor in the research and development of new drug candidates, particularly for targeted therapies.
• API Synthesis: Used in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs) for clinical trials and commercial production.
• Medicinal Chemistry Research: Enables the exploration of novel chemical space and structure-activity relationships (SAR) in drug discovery programs.
• Process Chemistry Development: Serves as a standard or starting material for optimizing scalable and efficient manufacturing routes for new chemical entities.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs supporting global pharmaceutical innovation pipelines.

Basic Information

Product Name	[1-(6-Methoxy-Pyrimidin-4-Yl)-Piperidin-3-Yl]-Methyl-Carbamic Acid tert-Butyl Ester
CAS No.	1353966-51-4
Molecular Formula	C17H26N4O3
Molecular Weight	334.42 g/mol
Synonyms	tert-Butyl N-[[1-(6-methoxypyrimidin-4-yl)-3-piperidyl]methyl]carbamate; Carbamic acid, N-[[1-(6-methoxy-4-pyrimidinyl)-3-piperidinyl]methyl]-, 1,1-dimethylethyl ester; 1,1-Dimethylethyl N-[[1-(6-methoxy-4-pyrimidinyl)-3-piperidinyl]methyl]carbamate; BOC-Protected [1-(6-Methoxy-Pyrimidin-4-Yl)-Piperidin-3-Yl]-Methyl-Amine; (1-(6-Methoxypyrimidin-4-yl)piperidin-3-yl)methyl tert-butylcarbamate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to verify identity, purity, and consistency. Certificates of Analysis (COA) are available upon request, detailing batch-specific results. Our quality management system is designed to meet the stringent requirements of pharmaceutical R&D and manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere or with desiccant for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.