Description

[1-(6-Methoxy-Pyrimidin-4-Yl)-Piperidin-4-Yl]-Carbamic Acid tert-Butyl Ester is a high-purity advanced pharmaceutical intermediate (API intermediate) with the CAS number 1353965-72-6. This compound is critical for the synthesis of complex active pharmaceutical ingredients, offering a defined chemical scaffold for further functionalization. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) for drug discovery and development.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in pharmaceutical R&D.
• Process Chemistry: Serves as a critical intermediate in the scale-up and optimization of synthetic routes for target molecules.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the production of specialized compounds for clients.
• Bioconjugation & Probe Development: Potential use in creating chemical probes or conjugates for biochemical and diagnostic applications due to its functional groups.
• Academic Research: Utilized in university and institutional labs for synthetic organic chemistry projects and novel methodology development.

Basic Information

Product Name	[1-(6-Methoxy-Pyrimidin-4-Yl)-Piperidin-4-Yl]-Carbamic Acid tert-Butyl Ester
CAS No.	1353965-72-6
Molecular Formula	C15H24N4O3
Molecular Weight	308.38 g/mol
Synonyms	tert-Butyl N-[1-(6-methoxypyrimidin-4-yl)piperidin-4-yl]carbamate; 1-(6-Methoxy-Pyrimidin-4-Yl)-Piperidin-4-Yl-Carbamic Acid tert-Butyl Ester; 4-[[(1,1-Dimethylethoxy)carbonyl]amino]-1-(6-methoxy-4-pyrimidinyl)piperidine; BOC-4-Amino-1-(6-methoxy-4-pyrimidinyl)piperidine; (1-(6-Methoxypyrimidin-4-yl)piperidin-4-yl)carbamic acid tert-butyl ester; 1353965-72-6; UNII-8G8W0J1J8I
EINECS	Contact for details

Quality Control

Our [1-(6-Methoxy-Pyrimidin-4-Yl)-Piperidin-4-Yl]-Carbamic Acid tert-Butyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.