Description

4-(6-Methoxy-2-Methylsulfanyl-Pyrimidin-4-Yloxymethyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a protected piperidine scaffold essential for constructing molecules with targeted biological activity. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Process Development: Serves as a critical starting material or intermediate in scaling up API manufacturing processes under GMP conditions.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule development.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and pharmacological studies.
• Protease Inhibitor Scaffolds: The structural motif is relevant for developing inhibitors targeting specific enzymatic pathways.

Basic Information

Item	Details
Product Name	4-(6-Methoxy-2-Methylsulfanyl-Pyrimidin-4-Yloxymethyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1353962-38-5
Molecular Formula	C17H27N3O4S
Molecular Weight	369.48 g/mol
Synonyms	tert-Butyl 4-[[(6-methoxy-2-methylsulfanyl-4-pyrimidinyl)oxy]methyl]piperidine-1-carboxylate; 1-Boc-4-((6-methoxy-2-(methylthio)pyrimidin-4-yloxy)methyl)piperidine; 4-((6-Methoxy-2-(methylthio)pyrimidin-4-yloxy)methyl)piperidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-((6-methoxy-2-(methylthio)pyrimidin-4-yloxy)methyl)piperidine; BOC-Piperidine-4-(6-Methoxy-2-Methylsulfanyl-Pyrimidin-4-Yloxymethyl) Ester
EINECS	Contact for details

Quality Control

Our production of 4-(6-Methoxy-2-Methylsulfanyl-Pyrimidin-4-Yloxymethyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.