Description

[1-(6-Methoxy-2-Methylsulfanyl-Pyrimidin-4-Yl)-Piperidin-4-Ylmethyl]-Carbamic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate designed for complex synthesis pathways. This compound matters for its role as a critical building block in the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic chemistry. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to create new molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides where the pyrimidine core structure is essential for bioactivity.
• Chemical Biology Research: Serves as a versatile scaffold or probe in medicinal chemistry programs for structure-activity relationship (SAR) studies.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial manufacturing of complex organic molecules.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	[1-(6-Methoxy-2-Methylsulfanyl-Pyrimidin-4-Yl)-Piperidin-4-Ylmethyl]-Carbamic Acid tert-Butyl Ester
CAS No.	1353958-76-5
Molecular Formula	C17H28N4O3S
Molecular Weight	368.50 g/mol
Synonyms	tert-Butyl N-[[1-(6-methoxy-2-methylsulfanylpyrimidin-4-yl)piperidin-4-yl]methyl]carbamate; 1-(6-Methoxy-2-(methylthio)pyrimidin-4-yl)piperidine-4-carboxylic acid tert-butyl ester (related structure); 4-[[(tert-Butoxycarbonyl)amino]methyl]-1-(6-methoxy-2-(methylthio)pyrimidin-4-yl)piperidine; BOC-Piperidine-Pyrimidine Intermediate; 1353958-76-5
EINECS	Contact for details

Quality Control

Our [1-(6-Methoxy-2-Methylsulfanyl-Pyrimidin-4-Yl)-Piperidin-4-Ylmethyl]-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.